![]() ![]() Research has shown that some people with certain genes are more likely to develop autoimmune disorders. It's not clear why some people develop this problem with their immune system, although it can run in families. ![]() Once levels of these start decreasing, you'll experience symptoms of Addison's disease. When 90% of the adrenal cortex is destroyed, your adrenal glands will not be able to produce enough of the steroid hormones cortisol and aldosterone. This is called an autoimmune disorder.Īddison's disease can develop if your immune system attacks your adrenal glands and severely damages your adrenal cortex. However, if you develop a problem with your immune system, it can start to attack your own healthy tissues and organs. These antibodies attack the cause of the illness. If you're ill, your immune system produces antibodies – a special type of protein that destroys disease-carrying organisms and toxins. The immune system is your body's defence against infection and disease. Problems with the immune systemĪ problem with the immune system is the most common cause of Addison's disease in the UK. Addison's disease develops when the outer layer of your adrenal glands (adrenal cortex) is damaged, reducing the levels of hormones it produces. ![]()
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